Epigen antibody (AA 23-110) (Fluoro488)

Catalog No. ABIN7988239

The Rabbit Polyclonal anti-Epigen antibody is suitable to detect Epigen in samples from Human and Rat. It has been validated for FACS.

Quick Overview for Epigen antibody (AA 23-110) (Fluoro488) (ABIN7988239)

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epigen antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Epigen Antibody (Fluoro488)

Binding Specificity: AA 23-110

Purpose: Anti-Epigen/EPGN Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Epigen recombinant protein (Position: A23-K110). Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Epigen recombinant protein (Position: A23-K110). Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Epigen

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Alternative Name: EPGN

Background:

Background: Epigen, also known as epithelial mitogen, is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Gene Full Name: epithelial mitogen

Gene ID: 255324

UniProt: Q6UW88

Pathways: RTK Signaling, EGFR Signaling Pathway