Epigen antibody (AA 23-110)

Catalog No. ABIN7988247

This Rabbit Polyclonal antibody specifically detects Epigen in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for Epigen antibody (AA 23-110) (ABIN7988247)

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epigen antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-Epigen Antibody

Binding Specificity: AA 23-110

Purpose: Anti-Epigen/EPGN Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Epigen recombinant protein (Position: A23-K110). Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Characteristics: Anti-Epigen/EPGN Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Epigen recombinant protein (Position: A23-K110). Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Epigen

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Alternative Name: EPGN

Background:

Background: Epigen, also known as epithelial mitogen, is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Gene Full Name: epithelial mitogen

Molecular Weight: 17 kDa

Gene ID: 255324

UniProt: Q6UW88

Pathways: RTK Signaling, EGFR Signaling Pathway