EDEM3 antibody (AA 54-795) (Biotin)

Catalog No. ABIN7988325

This Rabbit Polyclonal antibody specifically detects EDEM3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for EDEM3 antibody (AA 54-795) (Biotin) (ABIN7988325)

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-EDEM3 Antibody (Biotin)

Binding Specificity: AA 54-795

Purpose: Anti-EDEM3 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EDEM3 recombinant protein (Position: N54-D795).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EDEM3

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Alternative Name: EDEM3

Background:

Background: ER degradation-enhancing alpha-mannosidase-like 3 is an enzyme that in humans is encoded by the EDEM3 gene. Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER.

Gene Full Name: ER degradation enhancing alpha-mannosidase like protein 3

Gene ID: 80267

UniProt: Q9BZQ6

Pathways: SARS-CoV-2 Protein Interactome