ERLIN2 antibody (AA 87-339) (FITC)

Catalog No. ABIN7988352

This Mouse Monoclonal antibody specifically detects ERLIN2 in FACS. It exhibits reactivity toward Human.

Quick Overview for ERLIN2 antibody (AA 87-339) (FITC) (ABIN7988352)

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERLIN2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 3H9A2

Product Details anti-ERLIN2 Antibody (FITC)

Binding Specificity: AA 87-339

Purpose: Anti-Erlin-2/ERLIN2 Antibody (monoclonal, 3H9A2) FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Erlin-2/ERLIN2 recombinant protein (Position: D87-N339).

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: ERLIN2

Background:

Background: Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene. This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: ER lipid raft associated 2

Gene ID: 11160

UniProt: O94905