Espin antibody (AA 143-854) (Fluoro647)

Catalog No. ABIN7988466

This Rabbit Polyclonal antibody specifically detects Espin in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Espin antibody (AA 143-854) (Fluoro647) (ABIN7988466)

Target: Espin (ESPN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Espin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Espin Antibody (Fluoro647)

Binding Specificity: AA 143-854

Purpose: Anti-ESPN Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human ESPN shares 75.6%,78.1% amino acid (aa) sequence identity with mouse,rat ESPN,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ESPN recombinant protein (Position: H143-Y854). Human ESPN shares 75.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ESPN, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Espin

Target: Espin (ESPN)

Alternative Name: ESPN

Background:

Background: This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.

Gene Full Name: espin

Gene ID: 83715

UniProt: B1AK53

Pathways: Sensory Perception of Sound