Exonuclease 1 antibody (AA 1-294) (HRP)

Catalog No. ABIN7989282

This Rabbit Polyclonal antibody specifically detects Exonuclease 1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Exonuclease 1 antibody (AA 1-294) (HRP) (ABIN7989282)

Target: Exonuclease 1 (EXO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Exonuclease 1 Antibody (HRP)

Binding Specificity: AA 1-294

Purpose: Anti-Exonuclease 1/EXO1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: M1-K294).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1

Background:

Background: Exonuclease 1?is an?enzyme?that in humans is encoded by the?EXO1?gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

Gene Full Name: exonuclease 1

Gene ID: 9156

UniProt: Q9UQ84

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response