EXOSC3 antibody (AA 64-275) (Cy3)

Catalog No. ABIN7989343

The Rabbit Polyclonal anti-EXOSC3 antibody is suitable to detect EXOSC3 in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for EXOSC3 antibody (AA 64-275) (Cy3) (ABIN7989343)

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-EXOSC3 Antibody (Cy3)

Binding Specificity: AA 64-275

Purpose: Anti-EXOSC3 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EXOSC3 recombinant protein (Position: R64-S275).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EXOSC3

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Alternative Name: EXOSC3

Background:

Background: Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: exosome component 3

Gene ID: 51010

UniProt: Q9NQT5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome