FBXO7 antibody (AA 18-522) (Fluoro550)

Catalog No. ABIN7989489

This Rabbit Polyclonal antibody specifically detects FBXO7 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for FBXO7 antibody (AA 18-522) (Fluoro550) (ABIN7989489)

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-FBXO7 Antibody (Fluoro550)

Binding Specificity: AA 18-522

Purpose: Anti-FBXO7 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human FBXO7 shares 72.6%,72.1% amino acid (aa) sequence identity with mouse,rat FBXO7,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FBXO7 recombinant protein (Position: E18-M522). Human FBXO7 shares 72.6% and 72.1% amino acid (aa) sequence identity with mouse and rat FBXO7, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7

Background:

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Gene Full Name: F-box protein 7

Gene ID: 25793

UniProt: Q9Y3I1