FAM111B antibody (AA 328-726)

Catalog No. ABIN7989562

The Rabbit Polyclonal anti-FAM111B antibody is suitable to detect FAM111B in samples from Human. It has been validated for ELISA, IHC, WB and FACS.

Quick Overview for FAM111B antibody (AA 328-726) (ABIN7989562)

Target: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM111B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-FAM111B Antibody

Binding Specificity: AA 328-726

Purpose: Anti-FAM111B Antibody

Predicted Reactivity: Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.

Characteristics: Anti-FAM111B Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM111B recombinant protein (Position: Q328-D726). Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FAM111B

Target: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Alternative Name: FAM111B

Background:

Background: This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

Gene Full Name: FAM111 trypsin like peptidase B

Molecular Weight: 85 kDa

Gene ID: 374393

UniProt: Q6SJ93