Fatty Acid Synthase antibody (AA 1-226) (Fluoro647)

Catalog No. ABIN7990034

The Fluoro647-conjugated Rabbit Polyclonal anti-Fatty Acid Synthase antibody (ABIN7990034) specifically detects Fatty Acid Synthase in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Fatty Acid Synthase antibody (AA 1-226) (Fluoro647) (ABIN7990034)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Fatty Acid Synthase Antibody (Fluoro647)

Binding Specificity: AA 1-226

Purpose: Anti-Fatty Acid Synthase/FASN Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3%,90.7% amino acid (aa) sequence identity with mouse,rat FASN,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN

Background:

Background: Fatty acid synthase  (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Gene Full Name: fatty acid synthase

Gene ID: 2194

UniProt: P49327

Pathways: AMPK Signaling