FAP antibody (AA 65-580) (Fluoro550)

Catalog No. ABIN7990381

The Rabbit Polyclonal anti-FAP antibody is suitable to detect FAP in samples from Human. It has been validated for FACS.

Quick Overview for FAP antibody (AA 65-580) (Fluoro550) (ABIN7990381)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAP antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-FAP Antibody (Fluoro550)

Binding Specificity: AA 65-580

Purpose: Anti-Fibroblast activation protein, alpha/FAP Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibroblast activation protein, alpha/FAP recombinant protein (Position: Q65-Q580).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: FAP

Background:

Background: Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: fibroblast activation protein alpha

Gene ID: 2191

UniProt: Q12884

Pathways: Tube Formation