FGF1 antibody (AA 22-146) (FITC)

Catalog No. ABIN7990394

The FITC-conjugated Rabbit Polyclonal anti-FGF1 antibody (ABIN7990394) specifically detects FGF1 in FACS. The antibody is reactive with Human samples.

Quick Overview for FGF1 antibody (AA 22-146) (FITC) (ABIN7990394)

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-FGF1 Antibody (FITC)

Binding Specificity: AA 22-146

Purpose: Anti-FGF1 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human FGF1 shares 97% amino acid (aa) sequence identity with both mouse,rat FGF1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF1 recombinant protein (Position: N22-L146). Human FGF1 shares 97% amino acid (aa) sequence identity with both mouse and rat FGF1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Alternative Name: FGF1

Background:

Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor.

Gene Full Name: fibroblast growth factor 1

Sequence Similarities: Belongs to the heparin-binding growth factors family.

Gene ID: 2246

UniProt: P05230

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway