FGF10 antibody (AA 38-208) (Fluoro647)

Catalog No. ABIN7990431

This Rabbit Polyclonal antibody specifically detects FGF10 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FGF10 antibody (AA 38-208) (Fluoro647) (ABIN7990431)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF10 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-FGF10 Antibody (Fluoro647)

Binding Specificity: AA 38-208

Purpose: Anti-FGF10 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF10 recombinant protein (Position: Q38-S208).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Alternative Name: FGF10

Background:

Background: Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. It is mapped to 5p12. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Gene Full Name: fibroblast growth factor 10

Gene ID: 2255

UniProt: O15520

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus