FGF10 antibody (N-Term) (HRP)

Catalog No. ABIN7990439

The HRP-conjugated Rabbit Polyclonal anti-FGF10 antibody (ABIN7990439) specifically detects FGF10 in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for FGF10 antibody (N-Term) (HRP) (ABIN7990439)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF10 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FGF10 Antibody (HRP)

Binding Specificity: N-Term

Purpose: Anti-Fibroblast growth factor 10 FGF10 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FGF10, different from the related mouse and rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Alternative Name: FGF10

Background:

Background: FGF 10, Fibroblast growth factor 10, is a protein that in humans is encoded by the FGF10 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF 10 contains 3 exons and spans at least 52.7 kb. By radioactive in situ hybridization, the FGF 10 gene is mapped to 5p13-p12. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts. FGF 10 translocated into urothelial cell nuclei and initiated a signaling cascade that began with the heparin-dependent tyrosine phosphorylation of surface transmembrane receptors.

Gene Full Name: fibroblast growth factor 10

Sequence Similarities: Belongs to the heparin-binding growth factors family.

Gene ID: 2255

UniProt: O15520

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus