FGF23 antibody (AA 48-251) (APC)

Catalog No. ABIN7990594

The Rabbit Polyclonal anti-FGF23 antibody is suitable to detect FGF23 in samples from Mouse. It has been validated for FACS.

Quick Overview for FGF23 antibody (AA 48-251) (APC) (ABIN7990594)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF23 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-FGF23 Antibody (APC)

Binding Specificity: AA 48-251

Purpose: Anti-FGF23 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1%,94.6% amino acid (aa) sequence identity with human,rat FGF23,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1% and 94.6% amino acid (aa) sequence identity with human and rat FGF23, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: Fgf23

Background:

Background: Fibroblast growth factor 23?or?FGF23?is a?protein?that in humans is encoded by the?FGF23?gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Gene Full Name: fibroblast growth factor 23

Gene ID: 64654

UniProt: Q9EPC2

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion