FGF3 antibody (AA 18-239) (HRP)

Catalog No. ABIN7990615

The Rabbit Polyclonal anti-FGF3 antibody is suitable to detect FGF3 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for FGF3 antibody (AA 18-239) (HRP) (ABIN7990615)

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FGF3 Antibody (HRP)

Binding Specificity: AA 18-239

Purpose: Anti-FGF3 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF3 recombinant protein (Position: A18-H239).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FGF3

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Alternative Name: FGF3

Background:

Background: INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Gene Full Name: fibroblast growth factor 3

Gene ID: 2248

UniProt: P11487

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway