Fibromodulin antibody (AA 19-376) (Fluoro550)

Catalog No. ABIN7990789

The Rabbit Polyclonal anti-Fibromodulin antibody is suitable to detect Fibromodulin in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for Fibromodulin antibody (AA 19-376) (Fluoro550) (ABIN7990789)

Target: Fibromodulin (FMOD)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Fibromodulin Antibody (Fluoro550)

Binding Specificity: AA 19-376

Purpose: Anti-Fibromodulin/FMOD Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Fibromodulin,FMOD shares 93.3% amino acid (aa) sequence identity with both mouse,rat Fibromodulin,FMOD.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibromodulin/FMOD recombinant protein (Position: Q19-I376). Human Fibromodulin/FMOD shares 93.3% amino acid (aa) sequence identity with both mouse and rat Fibromodulin/FMOD.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD

Background:

Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Gene Full Name: fibromodulin

Gene ID: 2331

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process