Filaggrin antibody (AA 1-261) (PE)

Catalog No. ABIN7990861

The Rabbit Polyclonal anti-Filaggrin antibody is suitable to detect Filaggrin in samples from Human. It has been validated for FACS.

Quick Overview for Filaggrin antibody (AA 1-261) (PE) (ABIN7990861)

Target: Filaggrin (FLG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filaggrin antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Filaggrin Antibody (PE)

Binding Specificity: AA 1-261

Purpose: Anti-Filaggrin/FLG Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Filaggrin recombinant protein (Position: M1-R261).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Filaggrin

Target: Filaggrin (FLG)

Alternative Name: FLG

Background:

Background: In humans, profillagrin is encoded by the?FLG?gene, which is part of the S100 fused-type protein (SFTP) family within the?epidermal differentiation complex?on?chromosome 1q21. The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

Gene Full Name: filaggrin

Gene ID: 2312

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance