Frataxin antibody (AA 20-210) (HRP)

Catalog No. ABIN7991783

The HRP-conjugated Rabbit Polyclonal anti-Frataxin antibody (ABIN7991783) specifically detects Frataxin in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for Frataxin antibody (AA 20-210) (HRP) (ABIN7991783)

Target: Frataxin (FXN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Frataxin antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Frataxin Antibody (HRP)

Binding Specificity: AA 20-210

Purpose: Anti-FXN Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human FXN shares 79%,71.4% amino acid (aa) sequence identity with mouse,rat FXN,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FXN recombinant protein (Position: Q20-A210). Human FXN shares 79% and 71.4% amino acid (aa) sequence identity with mouse and rat FXN, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: FXN

Background:

Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Gene Full Name: frataxin

Gene ID: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size