Frataxin antibody (AA 20-210) (Fluoro647)
Quick Overview for Frataxin antibody (AA 20-210) (Fluoro647) (ABIN7991786)
Target
See all Frataxin (FXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-210
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Purpose
- Anti-FXN Antibody Fluoro647 Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- Human FXN shares 79%,71.4% amino acid (aa) sequence identity with mouse,rat FXN,respectively.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human FXN recombinant protein (Position: Q20-A210). Human FXN shares 79% and 71.4% amino acid (aa) sequence identity with mouse and rat FXN, respectively.
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Isotype
- IgG
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Application Notes
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Expiry Date
- 12 months
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- Frataxin (FXN)
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Alternative Name
- FXN
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Background
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Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Gene Full Name: frataxin
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Gene ID
- 2395
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UniProt
- Q16595
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
Target
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