FUS antibody (Middle Region) (Cy3)

Catalog No. ABIN7992023

The Cy3-conjugated Rabbit Polyclonal anti-FUS antibody (ABIN7992023) specifically detects FUS in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FUS antibody (Middle Region) (Cy3) (ABIN7992023)

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-FUS Antibody (Cy3)

Binding Specificity: Middle Region

Purpose: Anti-TLS/FUS Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TLS/FUS, identical to the related mouse sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS

Background:

Background: RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Gene Full Name: FUS RNA binding protein

Gene ID: 2521

UniProt: P35637