GRK1 antibody (AA 28-524) (Fluoro550)

Catalog No. ABIN7992202

The Rabbit Polyclonal anti-GRK1 antibody is suitable to detect GRK1 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for GRK1 antibody (AA 28-524) (Fluoro550) (ABIN7992202)

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-GRK1 Antibody (Fluoro550)

Binding Specificity: AA 28-524

Purpose: Anti-GRK1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GRK1 shares 86.9%,87.5% amino acid (aa) sequence identity with mouse,rat GRK1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GRK1 recombinant protein (Position: Q28-E524). Human GRK1 shares 86.9% and 87.5% amino acid (aa) sequence identity with mouse and rat GRK1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Alternative Name: GRK1

Background:

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).

Gene Full Name: G protein-coupled receptor kinase 1

Gene ID: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction