GRK1 antibody (AA 28-524)

Catalog No. ABIN7992209

The Rabbit Polyclonal anti-GRK1 antibody (ABIN7992209) specifically detects GRK1 in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for GRK1 antibody (AA 28-524) (ABIN7992209)

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Grade: Carrier-free

Product Details anti-GRK1 Antibody

Binding Specificity: AA 28-524

Purpose: Anti-GRK1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GRK1 shares 86.9%,87.5% amino acid (aa) sequence identity with mouse,rat GRK1,respectively.

Characteristics: Anti-GRK1 Antibody. Tested in WB, IHC, ELISA applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GRK1 recombinant protein (Position: Q28-E524). Human GRK1 shares 86.9% and 87.5% amino acid (aa) sequence identity with mouse and rat GRK1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Alternative Name: GRK1

Background:

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).

Gene Full Name: G protein-coupled receptor kinase 1

Molecular Weight: 64 kDa

Gene ID: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction