GLA antibody (C-Term) (Cy3)

Catalog No. ABIN7992366

This Rabbit Polyclonal antibody specifically detects GLA in FACS. It exhibits reactivity toward Human.

Quick Overview for GLA antibody (C-Term) (Cy3) (ABIN7992366)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-GLA Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-Galactosidase alpha/Gla Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Galactosidase alpha/Gla.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: GLA

Background:

Background: Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Gene Full Name: galactosidase alpha

Gene ID: 2717

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome