Galectin 3 antibody (AA 139-250) (Biotin)

Catalog No. ABIN7992442

The Mouse Monoclonal anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Galectin 3 antibody (AA 139-250) (Biotin) (ABIN7992442)

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 12B12

Product Details anti-Galectin 3 Antibody (Biotin)

Binding Specificity: AA 139-250

Purpose: Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12) Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human Galectin 3 shares 88%,84% amino acid (aa) sequence identity with mouse,rat Galectin 3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Galectin 3 recombinant protein (Position: K139-I250). Human Galectin 3 shares 88% and 84% amino acid (aa) sequence identity with mouse and rat Galectin 3, respectively.

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: LGALS3

Background:

Background: SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

Gene Full Name: galectin 3

Gene ID: 3958

UniProt: P17931

Pathways: RTK Signaling