Galectin 3 antibody (AA 129-250) (Biotin)

Catalog No. ABIN7992453

This Rabbit Polyclonal antibody specifically detects Galectin 3 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Galectin 3 antibody (AA 129-250) (Biotin) (ABIN7992453)

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Galectin 3 Antibody (Biotin)

Binding Specificity: AA 129-250

Purpose: Anti-LGALS3 Antibody Biotin Conjugated

Predicted Reactivity: Human Galectin-3,LGALS3 shares 87.7%,84.4% amino acid (aa) sequence identity with mouse,rat Galectin-3,LGALS3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Galectin-3/LGALS3 recombinant protein (Position: R129-I250). Human Galectin-3/LGALS3 shares 87.7% and 84.4% amino acid (aa) sequence identity with mouse and rat Galectin-3/LGALS3, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: LGALS3

Background:

Background: Galectin-3(GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21-q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

Gene Full Name: galectin 3

Gene ID: 3958

UniProt: P17931

Pathways: RTK Signaling