GSDMD antibody (AA 1-484) (Biotin)

Catalog No. ABIN7992839

The Biotin-conjugated Mouse Monoclonal anti-GSDMD antibody (Clone 3D5) (ABIN7992839) specifically detects GSDMD in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for GSDMD antibody (AA 1-484) (Biotin) (ABIN7992839)

Target: GSDMD (Gasdermin D (GSDMD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSDMD antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 3D5

Product Details anti-GSDMD Antibody (Biotin)

Binding Specificity: AA 1-484

Purpose: Anti-GSDMD Antibody (monoclonal, 3D5) Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GSDMD recombinant protein (Position: M1-H484).

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD

Background:

Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Gene Full Name: gasdermin D

Gene ID: 79792

UniProt: P57764

Pathways: Inflammasome