GFRA2 antibody (AA 30-425)

Catalog No. ABIN7993036

The Rabbit Polyclonal anti-GFRA2 antibody is suitable to detect GFRA2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC, IF and FACS.

Quick Overview for GFRA2 antibody (AA 30-425) (ABIN7993036)

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-GFRA2 Antibody

Binding Specificity: AA 30-425

Purpose: Anti-GFRA2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Characteristics: Anti-GFRA2 Antibody. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunofluorescence, 5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Alternative Name: GFRA2

Background:

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: GDNF family receptor alpha 2

Molecular Weight: 52 kDa

Gene ID: 2675

UniProt: O00451