GANAB antibody (AA 68-944) (APC)

Catalog No. ABIN7993528

The Rabbit Polyclonal anti-GANAB antibody is suitable to detect GANAB in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for GANAB antibody (AA 68-944) (APC) (ABIN7993528)

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANAB antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-GANAB Antibody (APC)

Binding Specificity: AA 68-944

Purpose: Anti-GANAB Antibody APC Conjugated

Predicted Reactivity: Human GANAB shares 92% amino acid (aa) sequence identity with mouse GANAB.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GANAB recombinant protein (Position: Q68-R944). Human GANAB shares 92% amino acid (aa) sequence identity with mouse GANAB.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GANAB

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Alternative Name: GANAB

Background:

Background: Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene. This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Gene Full Name: glucosidase II alpha subunit

Gene ID: 23193

UniProt: Q14697