GBA2 antibody (AA 17-869) (Biotin)

Catalog No. ABIN7993532

The Biotin-conjugated Rabbit Polyclonal anti-GBA2 antibody (ABIN7993532) specifically detects GBA2 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GBA2 antibody (AA 17-869) (Biotin) (ABIN7993532)

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-GBA2 Antibody (Biotin)

Binding Specificity: AA 17-869

Purpose: Anti-GBA2 Antibody Biotin Conjugated

Predicted Reactivity: Human GBA2 shares 88.5%,90.2% amino acid (aa) sequence identity with mouse,rat GBA2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GBA2 recombinant protein (Position: E17-Q869). Human GBA2 shares 88.5% and 90.2% amino acid (aa) sequence identity with mouse and rat GBA2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GBA2

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Alternative Name: GBA2

Background:

Background: GBA2 is the gene that encodes the enzyme non-lysosomal glucosylceramidase in humans. This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.

Gene Full Name: glucosylceramidase beta 2

Gene ID: 57704

UniProt: Q9HCG7