Glutathione Reductase antibody (AA 256-522) (PE)

Catalog No. ABIN7994214

This Rabbit Polyclonal antibody specifically detects Glutathione Reductase in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Glutathione Reductase antibody (AA 256-522) (PE) (ABIN7994214)

Target: Glutathione Reductase (GSR)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Reductase antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Glutathione Reductase Antibody (PE)

Binding Specificity: AA 256-522

Purpose: Anti-Glutathione Reductase/GSR Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: GSR

Background:

Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene Full Name: glutathione-disulfide reductase

Gene ID: 2936

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis