Glutathione Synthetase antibody (AA 1-456) (HRP)

Catalog No. ABIN7994443

The Rabbit Polyclonal anti-Glutathione Synthetase antibody is suitable to detect Glutathione Synthetase in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Glutathione Synthetase antibody (AA 1-456) (HRP) (ABIN7994443)

Target: Glutathione Synthetase (GSS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Glutathione Synthetase Antibody (HRP)

Binding Specificity: AA 1-456

Purpose: Anti-GSS Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GSSshares 88.2%,87.7% amino acid (aa) sequence identity with mouse,rat GSS,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GSS recombinant protein (Position: M1-H456). Human GSSshares 88.2% and 87.7% amino acid (aa) sequence identity with mouse and rat GSS, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background:

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Gene Full Name: glutathione synthetase

Gene ID: 2937

UniProt: P48637

Pathways: Warburg Effect