Glutathione Synthetase antibody (AA 1-456) (APC)

Catalog No. ABIN7994444

The APC-conjugated Rabbit Polyclonal anti-Glutathione Synthetase antibody (ABIN7994444) specifically detects Glutathione Synthetase in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Glutathione Synthetase antibody (AA 1-456) (APC) (ABIN7994444)

Target: Glutathione Synthetase (GSS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Glutathione Synthetase Antibody (APC)

Binding Specificity: AA 1-456

Purpose: Anti-GSS Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GSSshares 88.2%,87.7% amino acid (aa) sequence identity with mouse,rat GSS,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GSS recombinant protein (Position: M1-H456). Human GSSshares 88.2% and 87.7% amino acid (aa) sequence identity with mouse and rat GSS, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background:

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Gene Full Name: glutathione synthetase

Gene ID: 2937

UniProt: P48637

Pathways: Warburg Effect