Glutathione Synthetase antibody (AA 1-425)

Catalog No. ABIN7994458

The Rabbit Polyclonal anti-Glutathione Synthetase antibody is suitable to detect Glutathione Synthetase in samples from Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Glutathione Synthetase antibody (AA 1-425) (ABIN7994458)

Target: Glutathione Synthetase (GSS)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Glutathione Synthetase Antibody

Binding Specificity: AA 1-425

Purpose: Anti-GSS Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse GSSshares 88%,95.8% amino acid (aa) sequence identity with human,rat GSS,respectively.

Characteristics: Anti-GSS Antibody. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse GSS recombinant protein (Position: M1-E425). Mouse GSSshares 88% and 95.8% amino acid (aa) sequence identity with human and rat GSS, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background:

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Gene Full Name: glutathione synthetase

Molecular Weight: 52 kDa

Gene ID: 14854

UniProt: P51855

Pathways: Warburg Effect