Growth Hormone 1 antibody (AA 27-216) (Fluoro647)

Catalog No. ABIN7995458

The Fluoro647-conjugated Rabbit Polyclonal anti-Growth Hormone 1 antibody (ABIN7995458) specifically detects Growth Hormone 1 in FACS. The antibody is reactive with Rat samples.

Quick Overview for Growth Hormone 1 antibody (AA 27-216) (Fluoro647) (ABIN7995458)

Target: Growth Hormone 1 (GH1)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Growth Hormone 1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Growth Hormone 1 Antibody (Fluoro647)

Binding Specificity: AA 27-216

Purpose: Anti-Growth Hormone/GH1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat GH recombinant protein (Position: F27-F216).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: GH1

Background:

Background: Growth Hormone (GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. Rat GH shares 98 % amino acid sequence homology with mouse. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.

Gene Full Name: growth hormone 1

Sequence Similarities: Belongs to the heparin-binding growth factors family.

Gene ID: 24391

UniProt: P01244

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process