GHITM antibody (AA 1-345) (HRP)

Catalog No. ABIN7995488

The HRP-conjugated Rabbit Polyclonal anti-GHITM antibody (ABIN7995488) specifically detects GHITM in ELISA, WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GHITM antibody (AA 1-345) (HRP) (ABIN7995488)

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHITM antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GHITM Antibody (HRP)

Binding Specificity: AA 1-345

Purpose: Anti-GHITM Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GHITM recombinant protein (Position: M1-K345).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GHITM

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Alternative Name: GHITM

Background:

Background: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 orDERP2, is a mitochondrial protein which localizes in the inner membrane.GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.

Gene Full Name: growth hormone inducible transmembrane protein

Gene ID: 27069

UniProt: Q9H3K2

Pathways: SARS-CoV-2 Protein Interactome