GUCY2D antibody (AA 65-1103)

Catalog No. ABIN7995877

The Rabbit Polyclonal anti-GUCY2D antibody is suitable to detect GUCY2D in samples from Human. It has been validated for WB and ELISA.

Quick Overview for GUCY2D antibody (AA 65-1103) (ABIN7995877)

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY2D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-GUCY2D Antibody

Binding Specificity: AA 65-1103

Purpose: Anti-GUCY2D Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-GUCY2D Antibody. Tested in WB, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GUCY2D recombinant protein (Position: D65-S1103).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GUCY2D

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Alternative Name: GUCY2D

Background:

Background: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Gene Full Name: guanylate cyclase 2D, retinal

Molecular Weight: 120 kDa

Gene ID: 3000

UniProt: Q02846

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction