HBS1L antibody (AA 293-622) (Fluoro488)

Catalog No. ABIN7996079

The Fluoro488-conjugated Rabbit Polyclonal anti-HBS1L antibody (ABIN7996079) specifically detects HBS1L in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HBS1L antibody (AA 293-622) (Fluoro488) (ABIN7996079)

Target: HBS1L (HBS1-Like (HBS1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBS1L antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HBS1L Antibody (Fluoro488)

Binding Specificity: AA 293-622

Purpose: Anti-HBS1L Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HBS1L shares 96.4%,97% amino acid (aa) sequence identity with mouse,rat HBS1L,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HBS1L recombinant protein (Position: H293-K622). Human HBS1L shares 96.4% and 97% amino acid (aa) sequence identity with mouse and rat HBS1L, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HBS1L

Target: HBS1L (HBS1-Like (HBS1L))

Alternative Name: HBS1L

Background:

Background: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Gene Full Name: HBS1 like translational GTPase

Gene ID: 10767

UniProt: Q9Y450