Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (C-Term) antibody (Cy3)

Catalog No. ABIN7996881

This Rabbit Polyclonal antibody specifically detects Hemoglobin Alpha 1 + 2 in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (C-Term) antibody (Cy3) (ABIN7996881)

Target: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy3

Application: Flow Cytometry (FACS)

Product Details

Binding Specificity: C-Term

Purpose: Anti-Hemoglobin/HBA1/HBA2 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Hemoglobin/HBA1/HBA2, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Alternative Name: HBA1/HBA2

Background:

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Gene Full Name: hemoglobin subunit alpha 1

Gene ID: 3039, 3040

UniProt: P69905