HS2ST1 antibody (AA 71-356) (Cy3)

Catalog No. ABIN7996991

The Cy3-conjugated Rabbit Polyclonal anti-HS2ST1 antibody (ABIN7996991) specifically detects HS2ST1 in FACS. The antibody is reactive with Human samples.

Quick Overview for HS2ST1 antibody (AA 71-356) (Cy3) (ABIN7996991)

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS2ST1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-HS2ST1 Antibody (Cy3)

Binding Specificity: AA 71-356

Purpose: Anti-HS2ST1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HS2ST1 recombinant protein (Position: E71-N356).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HS2ST1

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Alternative Name: HS2ST1

Background:

Background: Heparan sulfate 2-O-sulfotransferase 1 is an enzyme that in humans is encoded by the HS2ST1 gene. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene Full Name: heparan sulfate 2-O-sulfotransferase 1

Gene ID: 9653

UniProt: Q7LGA3

Pathways: Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interactome