Hepsin antibody (AA 47-417) (Fluoro488)

Catalog No. ABIN7997234

The Fluoro488-conjugated Rabbit Polyclonal anti-Hepsin antibody (ABIN7997234) specifically detects Hepsin in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Hepsin antibody (AA 47-417) (Fluoro488) (ABIN7997234)

Target: Hepsin (HPN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hepsin antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Hepsin Antibody (Fluoro488)

Binding Specificity: AA 47-417

Purpose: Anti-Hepsin/HPN Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Hepsin,HPNshares 90%,89.2% amino acid (aa) sequence identity with mouse,rat Hepsin,HPN,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Hepsin/HPN recombinant protein (Position: D47-L417). Human Hepsin/HPNshares 90% and 89.2% amino acid (aa) sequence identity with mouse and rat Hepsin/HPN, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Hepsin

Target: Hepsin (HPN)

Alternative Name: HPN

Background:

Background: This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.

Gene Full Name: hepsin

Gene ID: 3249

UniProt: P05981

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound