Aurora Kinase C antibody (AA 51-150) (HRP)

Catalog No. ABIN750077

The Rabbit Polyclonal anti-Aurora Kinase C antibody has been validated for WB and ELISA. It is suitable to detect Aurora Kinase C in samples from Human and Mouse.

Quick Overview for Aurora Kinase C antibody (AA 51-150) (HRP) (ABIN750077)

Target: Aurora Kinase C (AURKC)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase C antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Aurora Kinase C Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Aurora C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Alternative Name: Aurora C

Background:

Synonyms: AURKC, AIE2, AIK3, AurC, AURKC, Aurora C, Aurora/Ipl1 related kinase 3, IPL-1, Aurora/Ipl1/Eg2 protein 2, EC 2.7.11.1, Serine threonine protein kinase 13, STK13, AURKC_HUMAN.

Background: The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Gene ID: 6795

Pathways: Cell Division Cycle, Maintenance of Protein Location