Homeobox A11 antibody (AA 74-245) (Biotin)

Catalog No. ABIN7998059

The Biotin-conjugated Rabbit Polyclonal anti-Homeobox A11 antibody (ABIN7998059) specifically detects Homeobox A11 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Homeobox A11 antibody (AA 74-245) (Biotin) (ABIN7998059)

Target: Homeobox A11 (HOXA11)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox A11 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Homeobox A11 Antibody (Biotin)

Binding Specificity: AA 74-245

Purpose: Anti-HOXA11 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HOXA11 shares 95% amino acid (aa) sequence identity with mouse HOXA11.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HOXA11 recombinant protein (Position: H74-R245). Human HOXA11 shares 95% amino acid (aa) sequence identity with mouse HOXA11.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Homeobox A11

Target: Homeobox A11 (HOXA11)

Alternative Name: HOXA11

Background:

Background: Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene. It is mapped to 7p15.2. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is involved in the regulation of uterine development and is required for female fertility. HOXA11 is essential for the development of the uterosacral ligaments, it has been found that women with pelvic organ prolapse may have weakened connective tissue due to changes in this signaling pathway. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Gene Full Name: homeobox A11

Sequence Similarities: Belongs to the Abd-B homeobox family.

Gene ID: 3207

UniProt: P31270