Homeobox A11 antibody (AA 74-245)

Catalog No. ABIN7998069

This Rabbit Polyclonal antibody specifically detects Homeobox A11 in WB, IHC, FACS and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Homeobox A11 antibody (AA 74-245) (ABIN7998069)

Target: Homeobox A11 (HOXA11)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox A11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-Homeobox A11 Antibody

Binding Specificity: AA 74-245

Purpose: Anti-HOXA11 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HOXA11 shares 95% amino acid (aa) sequence identity with mouse HOXA11.

Characteristics: Anti-HOXA11 Antibody. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HOXA11 recombinant protein (Position: H74-R245). Human HOXA11 shares 95% amino acid (aa) sequence identity with mouse HOXA11.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, RatImmunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human Immunocytochemistry, 0.5-1 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Homeobox A11

Target: Homeobox A11 (HOXA11)

Alternative Name: HOXA11

Background:

Background: Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene. It is mapped to 7p15.2. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is involved in the regulation of uterine development and is required for female fertility. HOXA11 is essential for the development of the uterosacral ligaments, it has been found that women with pelvic organ prolapse may have weakened connective tissue due to changes in this signaling pathway. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Gene Full Name: homeobox A11

Sequence Similarities: Belongs to the Abd-B homeobox family.

Molecular Weight: 35 kDa

Gene ID: 3207

UniProt: P31270