HAO1 antibody (AA 48-370) (Biotin)

Catalog No. ABIN7998598

The Rabbit Polyclonal anti-HAO1 antibody is suitable to detect HAO1 in samples from Mouse, Human and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for HAO1 antibody (AA 48-370) (Biotin) (ABIN7998598)

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAO1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-HAO1 Antibody (Biotin)

Binding Specificity: AA 48-370

Purpose: Anti-HAO1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human HAO1 shares 90.4%,90.7% amino acid (aa) sequence identity with mouse,rat HAO1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HAO1 recombinant protein (Position: K48-I370). Human HAO1 shares 90.4% and 90.7% amino acid (aa) sequence identity with mouse and rat HAO1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Alternative Name: HAO1

Background:

Background: Hydroxyacid oxidase (glycolate oxidase) 1 is a protein that in humans is encoded by the HAO1 gene. This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

Gene Full Name: hydroxyacid oxidase 1

Gene ID: 54363

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process