HCN2 antibody (AA 660-863) (PE)

Catalog No. ABIN7998925

The Rabbit Polyclonal anti-HCN2 antibody is suitable to detect HCN2 in samples from Rat and Mouse. It has been validated for FACS.

Quick Overview for HCN2 antibody (AA 660-863) (PE) (ABIN7998925)

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCN2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-HCN2 Antibody (PE)

Binding Specificity: AA 660-863

Purpose: Anti-Hcn2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Hcn2 shares 87.4%,97.5% amino acid (aa) sequence identity with human,rat HCN2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Hcn2 recombinant protein (Position: E660-L863). Mouse Hcn2 shares 87.4% and 97.5% amino acid (aa) sequence identity with human and rat HCN2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HCN2

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Alternative Name: Hcn2

Background:

Background: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 is a protein that in humans is encoded by the HCN2 gene. The HCN2 gene is localized on human chromosome 19p13.3 and contains eight exons spanning approximately 27 kb. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain.

Gene Full Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2

Gene ID: 15166

UniProt: O88703