IDUA antibody (AA 1-87)
Quick Overview for IDUA antibody (AA 1-87) (ABIN7999070)
Target
See all IDUA AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 1-87
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Purpose
- Anti-IDUA Antibody
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Cross-Reactivity (Details)
- No cross reactivity with other proteins.
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Characteristics
- Anti-IDUA Antibody. Tested in ELISA, IF, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human INSIG1 recombinant protein (Position: M1-R87).
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- IDUA (Iduronidase, alpha-L- (IDUA))
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Alternative Name
- IDUA
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Background
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Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
Gene Full Name: alpha-L-iduronidase
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Molecular Weight
- 73 kDa
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Gene ID
- 3425
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UniProt
- P35475
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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