IRGM antibody (AA 50-333) (HRP)

Catalog No. ABIN7999165

The Rabbit Polyclonal anti-IRGM antibody is suitable to detect IRGM in samples from Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for IRGM antibody (AA 50-333) (HRP) (ABIN7999165)

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRGM antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IRGM Antibody (HRP)

Binding Specificity: AA 50-333

Purpose: Anti-IRGM/Irgm1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse IRGM/Irgm1 recombinant protein (Position: E50-K333).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IRGM

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Alternative Name: Irgm1

Background:

Background: Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is IRGM gene. This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: immunity-related GTPase family M member 1

Gene ID: 15944

UniProt: Q60766