IST1 antibody (AA 31-331) (Cy3)

Catalog No. ABIN7999303

The Rabbit Polyclonal anti-IST1 antibody is suitable to detect IST1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for IST1 antibody (AA 31-331) (Cy3) (ABIN7999303)

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IST1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-IST1 Antibody (Cy3)

Binding Specificity: AA 31-331

Purpose: Anti-hIST1/IST1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human IST1 shares 94%,93.1% amino acid (aa) sequence identity with mouse,rat IST1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human hIST1/IST1 recombinant protein (Position: E31-D331). Human IST1 shares 94% and 93.1% amino acid (aa) sequence identity with mouse and rat IST1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IST1

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Alternative Name: IST1

Background:

Background: IST1 homolog is a protein that in humans is encoded by the KIAA0174 gene. This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: IST1 factor associated with ESCRT-III

Gene ID: 9798

UniProt: P53990

Pathways: Regulation of Cell Size