Indian Hedgehog antibody (AA 227-360) (APC)

Catalog No. ABIN7999321

The Rabbit Polyclonal anti-Indian Hedgehog antibody is suitable to detect Indian Hedgehog in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Indian Hedgehog antibody (AA 227-360) (APC) (ABIN7999321)

Target: Indian Hedgehog (IHH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Indian Hedgehog Antibody (APC)

Binding Specificity: AA 227-360

Purpose: Anti-IHH Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human IHH shares 94.8% amino acid (aa) sequence identity with mouse IHH.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IHH recombinant protein (Position: D227-A360). Human IHH shares 94.8% amino acid (aa) sequence identity with mouse IHH.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: IHH

Background:

Background: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.

Gene Full Name: Indian hedgehog signaling molecule

Gene ID: 3549

UniProt: Q14623

Pathways: Hedgehog Signaling